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Then acetaldehyde is converted to acetate and water by aldehyde dehydrogenase (ALDH)

[PubMed] [Google Scholar] [38].Miller JC, Thomson CD, Williams SM, van Havre N, Wilkins GT, Morison IM, Ludgate JL, Skeaff CM, Influence of the glutathione peroxidase 1 Pro200Leu polymorphism on the response of glutathione peroxidase activity to selenium supplementation: a randomized controlled trial

However, under oxidative stress, oxidative modification of cysteine residues in Keap1 causes conformational changes that weaken its binding to Nrf2, allowing Nrf2 to dissociate from Keap-1 and rapidly translocate to the nucleus

Nonetheless, the effectiveness, safety, and advantages of prolonged metformin use during pregnancy in patients with PCOS remain a topic of significant debate in the medical field