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Emerging efforts to evaluate the role of the susceptibility loci for pulmonary fibrosis have led to unexpected results, as demonstrated by the discovery of the association of MUC5B variant with disease risk, but improved disease prognosis

Written by: Syed Mohasin, M

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Disulfide-containing linkers are primarily linked to maytansinoid payload classes, and the reactivity of disulfide bonds can be regulated by steric hindrance: alpha methyl substitution significantly affects reduction rate and resistance to thiol-disulfide exchange force

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