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Description
Cytosolic mtDNA activates the cGAS-STING axis, driving type I interferon responses and pro-inflammatory cytokine production, whereas extracellular or endolysosomal mtDNA stimulates toll-like receptor 9 (TLR9), leading to NF-B dependent inflammatory transcriptional programs
T., Stephens, F
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10.1093/cvr/cvaa094 19
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