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By stimulating the white-to-brown conversion hormonally, we observed that a rapid drop of GSH concentration and decreased GSH/GSSG ratio accompany the up-regulation of brown-related genes and that such an event is significantly blunted by supplementing adipocytes with GSH ester

, Yoon J

Of utmost importance is to further present the free radical scavenging properties of melatonin, as these protect against mitochondrial DNA damage induced by reactive oxygen species (ROS) displaying another of its significant effects on mitochondrial homeostasis (24,92,93)

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(September 1989)

This cellular enzyme protects against oxidative stress by deactivating reactive oxygen species (ROS)