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However, it should be noted that CXCR2 inhibition triggers side effects similar to those exhibited by the use of glucocorticoids, such as promoting bacterial/fungal infection and delaying wound healing

315,316 In a mouse asthma model, transgenic overexpression of Trx significantly reduced MIF expression in the airway epithelial cells and reduced the number of MIF-positive inflammatory cells in the lung parenchyma

Elevated homocysteine causes excessive clotting which diminishes blood flow to major regions of the body

This work was financially supported by national funds from Fundao para a Cincia e a Tecnologia, I.P

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