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The protocols of the EVINCI and SMARTool studies were approved by all local ethics committees, all patients gave their written informed consent to participate, and the procedures followed were in accordance with institutional guidelines

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elegans survey core cellular processes, and the disturbance of these vital processes by microbial effectors triggers widespread activation of cytoprotective stress, detoxification, and innate immune responses, called surveillance or effector-triggered immunity, as well as behavioral aversion 38,39,40,41

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