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The PALOMA-3 study demonstrated that the mOS of the palbociclib combined fulvestrant group was higher than that of the fulvestrant group (34.9 m vs 28.0 m)

The pathological section of HE in present study has shown that compared with the PBS group, most of the collagen fibers in high dose group are crimped seriously, the shape is irregular, and the arrangement is disordered

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Among them, the two studies showed alterations in Glu 18 and Gln 16 levels in the anterior cingulate cortex (ACC)