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Concerning the brain, it forms 2% of total body weight with high levels of fatty acids, uses 20% of total body oxygen, and has lower antioxidant activity than other tissues

This triggers the release of harmful cytokines like IL-8 and MCP-1, which stiffen arteries, raise blood pressure, and ultimately damage your kidneys
Exosomes: composition, biogenesis and function

Diabetes is a substantial and controllable standalone contributing factor for the onset of cardiovascular disease (CVD)

doi: 10.1097/MCC.0000000000000737
