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Finally, aging induces a shift in baseline serum antibody specificity, with an increased prevalence of autoreactive antibodies, such as those targeting cardiolipin, DNA, and antinuclear antibodies (ANA), as well as rheumatoid factor
Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology

Its rich phytochemical composition and traditional therapeutic use supported its selection as a promising natural candidate for molecular docking, ADME evaluation, and further drug discovery studies targeting neurological disorders

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It also appears to have reduced the aortic expression of both interferon-gamma and macrophage migration inhibitory factors

In vitro studies demonstrated that TH-positive neurons were highly susceptible to the toxic effect of Homocysteine (Heider et al
