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J Immunol (2008) 181(7):501523.10.4049/jimmunol.181.7.5015 32 LuBAntoineDJKwanKLundbckPWhmaaHSchierbeckHet alJAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

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Both immunocompetent and immunocompromised individuals are susceptible to extrapulmonary TB, although individuals living with HIV bear a heightened risk for extrapulmonary manifestations, particularly within the lymphatic system, with widespread dissemination, and affecting the central nervous system (CNS) (209)

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