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doi:10.1007/s12010-016-2335-x [DOI] [PubMed] [Google Scholar] 18.Ahn JY, Kim J, Cheong DH, Hong H, Jeong JY, Kim BG

doi:10.1111/bcp.12736

The GSH/GSSG ratio is a widely accepted indicator of oxidative stress and cellular redox balance

10.14715/cmb/2022.69.1.9

The results of the present study clearly point out that increasing corticosterone levels indicate that aspartame acts as a chemical stressor and that aspartame metabolite could accelerate lipid peroxidation leading to an increase in oxidative stress and altered cytokine secretion

Even though these clinical reports showed that slow acetylators have a higher risk of INH-induced liver injury with INH treatment in different populations77, 80, 81, 86, several other clinical observations showed modest or no significant difference of incidence of INH hepatotoxicity between different acetylators status87, 88, 89