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This is typically a normal physiological response rather than a direct toxic effect

Read the full study: The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and 3-AR knock-out mice (Endocrinology 2001)

Neither approach is inherently better

These effects are believed to be related to the broader systemic benefits of optimized GH circulation on brain function and hormonal balance

[DOI] [PubMed] [Google Scholar] 34.Heffernan MA, Jiang WJ, Thorburn AW, Ng FM: Effects of oral administration of a synthetic fragment of human growth hormone on lipid metabolism