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10.1016/j.chom.2018.05.004 Cell Host Microbe
Children's requirements are lower and increase with age: infants aged 0-6 months have a safe intake of about 0.3 g daily, those aged 712 months need 0.4 g daily, children aged 13 years require 0.5 g, those aged 46 years need 0.8 g, and children aged 710 years should receive 1.0 g daily

In people with reduced ALDH2 levels (and thus more acetaldehyde), alcohol is more likely to induce asthma.[ref] One study explains: Impaired ALDH2 activity leads to high peak levels of acetaldehyde and to histamine release. Studies show that inhaling acetaldehyde induces histamine-mediated airway constriction, such as is seen in asthma.[ref] Hangovers and histamine A recent animal study sheds light on the age-old question of what causes hangover symptoms

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These studies have contributed to understanding the potential role of NNMT in metabolic disorders

A day on the lake in the Arizona sun can lead to significant dehydration
