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As discussed above, numerous studies have reported efficacy of both agonists and PAMs of mGlu 2 to decrease taking and seeking of various drugs of abuse, lending support to the idea that despite adaptations in mGlu 2 function caused by chronic drug exposure, pharmacological interventions remain a viable strategy for correcting drug-related behaviors

Haloperidol-induced PD mice models (Swiss albino mice) were utilized for the in vivo assessment through intranasal administration of the prepared nanoparticles

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Relief from Muscle Pain and Cramps: B vitamins, especially *B1* and *B6*, contribute to muscle function and can help reduce the frequency and intensity of muscle cramps and pain, particularly when these symptoms are linked to nerve irritation or metabolic issues