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Researchers attributed these outcomes to the combined effects of telomere maintenance, improved antioxidant enzyme expression (including superoxide dismutase and glutathione peroxidase), and reduced incidence of spontaneous tumor development in treated groups

The accumulation of these heavy metals led to an increase in metallothionein protein concentration, lipid peroxidation, and the activity of antioxidant enzymes in the mycelium, enhancing the fungus's tolerance to heavy metal toxicity

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This allowed the antibodies to be broadly applicable (1327, 1414)

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