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However, folic acid does not prevent neurological symptoms, and without proper treatment with vitamin B12, irreversible damage may occur

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Future medicinal chemistry efforts may yield next-generation compounds with enhanced properties, including improved tissue selectivity, modified pharmacokinetics, or additional mechanistic activities that complement NNMT inhibition

Many patients with pernicious anaemia are treated with lifelong intramuscular vitamin B12 replacement

Vitamin B12 plays some very important roles in our bodies