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Description
Hi-C contact map biases were corrected using the ICE method, with normalization repeated 30 times 84
The mice were euthanized on day 38 after tumor implantation

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The enhanced drug bioavailability caused by piperine is due to its potent inhibition of drug metabolism, being able to inhibit human P-glycoprotein and CYP3A4, while it interferes with UDP-glucose dehydrogenase and glucuronidation activities in liver