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118 In accordance with this notion, ATII was shown to increase mitochondrial ROS production in a Nox-dependent manner 119 and vice versa
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Pyocyanin also initiates neutrophil extracellular trap (NET) formation (Rada et al., 2013) and aberrant NET release triggered by pyocyanin-mediated intracellular ROS production directly damages host tissues and has been linked to the severity of many diseases including CF (Rada et al., 2013)
Ellis, J
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