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Your prescribed injection method and dosage are determined by your doctor and provided by your pharmacy

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Intervention For the first 2 months, the subjects were instructed to take oral TA 250 mg twice daily and apply TCC composed of 5% hydroquinone, 0.003% tretinoin, and 1% hydrocortisone (Melanon cream, DONG-A ST, Korea) to the entire face once a day for 8 weeks