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10.1016/j.freeradbiomed.2018.10.451

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Abstract Conditioning of the bone marrow prior to haematopoietic stem cell transplant is essential in eradicating the primary cause of disease, facilitating donor cell engraftment and avoiding transplant rejection via immunosuppression

In a 72-week, double-blind phase 2 trial in patients with biopsy-confirmed NASH (legacy term) and fibrosis stage F1F3, once-daily subcutaneous semaglutide produced dose-dependent NASH resolution: 59% at the 0.4 mg dose versus 17% with placebo (a statistically significant difference)