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Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies

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Modulador de expresin gnica de amplio espectro : estudios transcriptmicos (Pickart et al., Biomed Res Int 2015) demuestran que GHK-Cu modula la expresin de ms de 4,000 genes humanos (15% del genoma codificante), reseteando perfiles transcripcionales hacia patrones de tejido joven