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These findings suggest that NAC should be used at a dose 1200 mg/day to prevent exacerbations in patients with a chronic bronchitis phenotype of COPD and airway obstruction, while regular doses (600 mg/day) may be sufficient in the absence of airway obstruction [37]

PMID: 304 JiaLLZhengQYTianJHHeDLZhaoJXZhaoLPet al

Follistatin (FST) is a glycoprotein predominantly secreted by the liver and expressed in various tissues, functioning to inhibit TGF- superfamily members

doi: 10.1002/14651858.CD004381.pub3 24 HanV

However, it is unclear whether NCOA4 can bind to the cell membrane before translocating to the cytoplasm, apart from the evidence demonstrating its truncated isoform SRC3s ability to bind to the cell membrane [44]

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