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The available information is based partly on their distribution in various types of cell and partly on their physical properties, but also on the effects of changes that occur in plasmalogen metabolism in certain mutant cells

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In fact, aged PI-PLC3-null mice typically have increased numbers of hematopoietic stem cells and myeloid progenitors in bone marrow and spleen, and their hematopoietic stem cells show an increased proliferation and a reduced apoptosis that have been molecularly associated with Stat5 inhibition (75)

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