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A., Hewish, M., Sims, D., Lord, C

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Results show that Mito 10 -NAC is nearly 15002000 times more potent than NAC, and that methylation of the free sulfhydryl group enhanced its antiproliferative effect (the half maximal inhibitory concentration [IC 50 ] for Mito 10 -MeNAC is 1.9 M compared with 9.6 M for Mito 10 -NAC), indicating that the antiproliferative effect is not related to the antioxidant or radical scavenging mechanism

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J Neurol Neurosurg Psychiatry 69: 4853, 2000