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K252a (TrkB block, 0.25 mg/kg i.p.)

Singh SB, Lin HC

Cowan CM, Roskams AJ

In view of the relationship between HCN channels and neuronal excitability in the modulation of cognitive function, the present study hypothesized that Iva could possess a therapeutic effect against Sco models of dementia, based on HCN blockage mechanisms in cerebral areas related to cognitive functions

It is thought to cause much of the inter-individual variations seen in drug responses, adverse effects, and interactions with drugs (83)

View Abstract "Sandwich" plating for intra-articular distal radius fractures with volar and dorsal metaphyseal comminution