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SHP2 is thought to also play a role during embryonic development by preventing the formation of AChR clusters in extra-synaptic sites that are not directly in contact with the motor nerve terminal (Qian et al., MuSK AntibodiesDiscovery and Pathogenicity Studies The constant and finely-tuned activation of the agrin-LRP4-MuSK-DOK7 pathway maintains the AChRs in high-density clusters on the post-synaptic membrane that is vital for the correct function of the NMJ

Tomatoes Tomatoes, a staple in many diets, contain about 64 nm of glutathione per gram

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and resulted in an oxidative-damage regenerative loop