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Chemotherapy with drugs like 5-fluorouracil has also been associated with acute thiamine deficiency by disrupting thiamine activation, so oncology patients receiving such therapy might receive parenteral thiamine supplementation as part of this B-Complex if needed

doi: 10.1038/oby.2009.184

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However, even those with normal levels of vitamin B12 will be able to notice and reap the benefits provided by vitamin B12/MIC shots, as the additional ingredients provide the following benefits as well: MIC (methionine, inositol, and choline) are all amino acids that are essential in maintaining muscle tissue, which is very important for healthy recovery from exercise during weight loss