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CoA is also considered to be extremely stable, as mice on B5-deficient diets for as long as 2 months do not show significant loss of CoA 10

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For skin, the primary mechanisms include stimulation of collagen I and III synthesis, increased production of decorin (which organizes collagen fibers), upregulation of VEGF for blood vessel formation, and activation of tissue remodeling through metalloproteinase regulation

Kalghatgi, S., Fridman, A., Azizkhan-Clifford, J

Proc Natl Acad Sci USA 97:75977602
