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To be more specific, periappendiceal fat stranding and appendiceal wall enhancement defect showed highest sensitivity, while extraluminal appendicolith, abscess, and extraluminal air showed highest specificity

Key points Incretins have an important role in glucose homeostasis, regulation of appetite, energy expenditure and immunity

Acknowledgements We thank Professors Brenda Schulman and Danny Nedialkova at MPIB for reagents, and Sabine Suppmann and the MPIB Protein Production Core Facility for LIF

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