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Science 313, 10721077 (2006)

What is our utility capacity and what will our needs be in the future

Cross-trial comparisons with dual-agonist agents such as tirzepatide are exploratory only no head-to-head trials have been conducted and should be interpreted with caution

A second model additionally included use of lipid-lowering agents, use of ACE inhibitors or angiotensin receptor blockers, use of any anti-hypertensive medication and use of insulin or oral hypoglycaemic agents (yes/no) (model 2)
Usdin TB, Mezey E, Button DC, et al

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