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Serving as key regulatory carriers in the progression of OSA-associated lung cancer, they modulate tumor cell proliferation, drug resistance, and immune responses within the TME (Jeppesen et al., 2019)
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Based on a comparison among multiple species, all OATPs/Oatps (rat) transport using a rocker-switch type of mechanism, where substrate passes through a central, positively charged pore (Roth et al., 2012

10.1016/j.neuron.2014.12.007 54

Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension
Pedersen, B
