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Finally, we show that intratumoural delivery of our senolytic and a Braf inhibitor can successfully eliminate early melanomas in a mouse model resulting in increased survival and systemic delivery of our senolytic can eliminate senescent cells in old mice

Chrubasik, S., Pittler, M., Roufogalis, B

reported that a mutation in RF2 (threonine 246 to alanine) allowed to knockout RF1 in certain E

Targeting private neoantigens requires the development of personalized therapies such as custom cancer vaccines and T cell-based therapies

Tau pathology and neurodegeneration contribute to cognitive impairment in Alzheimers disease