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Direct and indirect effects of pathogenic bacteria on the integrity of intestinal barrier

Successful clinical translation will depend on identifying predictive biomarkers, optimizing the timing and sequence of combination therapies, and developing agents capable of selectively modulating these pathways within the tumor microenvironment
Nature 2021;593:42934

Clinical research on anti-thrombotic therapy involving canakinumab has investigated the role of IL-1 in the induction of atherosclerosis

Development of a new reporter gene systemdsRed/xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2
