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Conversely, elevated IL-22 expression promotes the aggregation of B cells and the formation of lymphoid aggregates, resulting in the upregulation of multiple cytokines including CXCL12 and CXCL13, ultimately leading to the production of autoantibodies (52)

doi:10.1002/hep.30224 14

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Some of the symptoms include: tingling or numbness in the hands, feet or legs cognitive difficulties or memory loss a swollen, inflamed tongue difficulty walking/balance issues anaemia depression weakness fatigue The only way to know for sure is through a blood test
