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351,352 Similarly, EZH2 suppresses autophagy to drive tumor growth, whereas HDAC inhibition in neurons can reverse ATG silencing to restore proteostasis

In humans, copper transporters ATP7 and ATP7B play a critical role in copper transport in TGN network and result in Menkes disease or WD, respectively, when mutated

In reality, detoxification is not a short-term event

Reference Coruh, Celep, zgke and can2007b)

All-optical Spatiotemporal mapping of ROS dynamics across mitochondrial microdomains in situ [J]