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doi:10.1038/onc.2014.338 Macho A, Hirsch T, Marzo I et al (1997) Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis

Research Highlights Lifespan Extension: Increased lifespan in CBA and SAMP-1 mice compared to controls 1

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These efforts were spearheaded by US patient support groups that have urged the National Institutes of Health to fund research studies to better understand IC/BPS pathophysiology and to fund clinical studies to identify valid treatment approaches