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The pathophysiology of synaptic loss and neurodegeneration involves problems in the cleavage of the amyloid precursor protein (APP) with the production of APP beta-amyloid (A) fragment, together with the aggregation of the hyperphosphorylated tau protein

What makes therapeutic peptides compelling for longevity science is their specificity: unlike small-molecule drugs, which often bind promiscuously to multiple receptor types, peptides tend to interact with highly selective targets, producing narrower and more predictable biological effects [1]

Moreover, in spite of all the known properties desired in an ideal chelator the predictability of the outcome is limited

In the oxidative phosphorylation pathway, metabolites of glutamine participate in the generation of an electron donor, such as NADH or FADH 2 , after synthesis of guanosine triphosphate (GTP) and adenosine triphosphate (ATP)

The development of biomimetic and electroactive hybrid systems further expands the biomedical scope of stimuli-responsive nanomaterials

Molecular Formula: C20H32N6O12S2