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There is also ongoing debate about the most suitable product categorywhether food, supplement, or drugand about how to standardize measures of potency, viability, and functional outputs for strains whose benefits may vary significantly depending on context, including baseline microbiome, diet, and host genetics
Apr 2009;87(4):275-286
doi: 10.1179/1476830512Y.0000000043
Risk-of-bias assessment of the 19 cohort studies using ROBINS-I tool does show a moderate to a critical risk of bias

Silybum marianum has been used in western herbal medicine as a hepatoprotective and antioxidant

doi: 10.1021/bi00903a025
