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Given that absorption through the gastrointestinal tract can be impaired in some individuals, injections provide a reliable alternative to oral supplements

The epidemiology, economic burden, and pharmacological treatment of chronic low back pain in France, Germany, Italy, Spain and the UK: a literature-based review

2009b;136:179186

Initial response time also depends on: Severity of the B12 deficiency Frequency of injections Underlying health conditions Absorption and metabolism differences If youre getting your first B12 shot, your provider may start you on a more aggressive schedule, such as weekly injections until your levels are normalized

10.1186/s12974-018-1374-3 66 OsadchiyV.MartinC