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Animal experiments were approved by the Animal Care and Use Committee of Renmin Hospital of Wuhan University (WDRM 20200604), which complied with the Guide for the Care and Use of Laboratory Animals (NIH Publication No

Further purification was done by means of analytical HPLC on a 250 4.6 mm, 4 m, 90 A, Jupiter Proteo column (Phenomenex)

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Afr J Agric Res 6(9):20262032 Arafa MG, Ghalwash D, El-Kersh DM, Elmazar MM (2018) Propolis-based niosomes as oromuco-adhesive films: a randomized clinical trial of a therapeutic drug delivery platform for the treatment of oral recurrent aphthous ulcers