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Stress, overconsumption of alcohol, food intolerance, microbial imbalance and poor nutrition can affect the integrity of the epithelial barrier

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Smoking impairs vascular endothelial function and leads to atherosclerosis

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Disproportionality analysis, using algorithms like Reporting Odds Ratio (ROR) and Bayesian Confidence Propagation Neural Network (BCPNN), identified AE signals