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doi: 10.1016/j.jep.2012.10.045

In this study, we investigated the skin toxicity of several copper compounds using cell-based in vitro tests and evaluated the expression of various cytokines at genomic and proteomic levels to discover irritancy biomarkers suitable for copper compounds

In female mice, there were dose-related increases in the incidences of pituitary gland adenoma and carcinoma, and mammary gland adenocarcinoma at all doses tested (50 to 200 mg/kg/day or 1 to 5 times the MRHD based on mg/m2 body surface area)

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Instead it lightens dark spots by causing exfoliation

Beyond 12 weeks sustained planning typically rotates between SubQ phases and oral precursor bridges