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But they can still interact with T-cells to induce tolerance

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DKK1 antagonises Wnt signalling by disassembling synapses through the activation of the GSK-3 and Rock pathways

That is a bit of a catch-22 because B12 is essential for the intestines to be able to function optimally, but they cannot absorb it (from the food) when they are damaged or diseased

It opens the possibility of delivering remyelination-promoting peptides like TB4 or neuroprotective peptides like BPC-157 directly to MS lesions at concentrations that might not be achievable through systemic administration