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Clinically, strategies aimed at modulating EAAC1-mediated cysteine transport and boosting endogenous GSH synthesis may hold promise for mitigating post-ischemic neurodegeneration and cognitive deficits associated with vascular dementia

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Erythrocytes lack gamma-glutamyl transpeptidase and this enzyme activity also varies in other tissues

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Interestingly, inhibition of ferroptosis can usually be detected once upon sorafenib resistance occurs

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Pyroglutamate may be a promising therapeutic candidate for cognitive dysfunction in schizophrenia and other conditions with glutathione disturbances

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For pilot studies or budget-constrained projects where oral administration isn't a factor, the acetate salt remains a viable and economical choice

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