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But the angiogenic mechanism is real, and until there's human data we treat active cancer as an absolute contraindication

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2019 Jun Alejandro A Nava-Ocampo, Aleksandra Pastrak, Tony Cruz, Gideon Koren

[2] For this reason, elevated serum homocysteine over 15 micromol/L and methylmalonic acid (MMA) over 0.271 micromol/L are considered better indicators of B 12 deficiency, rather than relying only on the concentration of B 12 in blood

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