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Vitamin B12 functions in the body through two bioactive coenzymes: Methylcobalamin Functions in the cell plasma as a coenzyme in the methylation cycle Adenosylcobalamin Functions in the mitochondria as a coenzyme in the citric acid cycle Through these two functional mechanisms, multiple effects take place in diverse biological systems as explored in our article: Vitamin B12 Benefits The focus of this article is on methylcobalamin and its working within the methylation cycle