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In the Cagrilintide groups, observed mean weight losses ranged from 5.0% to 9.8% at week 32, slightly less than the 6.1% to 10.8% observed at week 26

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Data Availability Statement All relevant data are contained in this manuscript.

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*Correspondence: Chun Fang, [email protected] These authors have contributed equally to this work This article was submitted to Food Microbiology, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

5 similarly consider alpha-synuclein positivity using the alpha-synuclein SAA from CSF or skin biopsies, as well as neurodegeneration, measured with imaging including dopaminergic PET/SPECT