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In particular, genetically predicted albumin was obviously associated with lower chances of PD (OR = 0.874, p = 0.037), and higher chances of AD in IVW analysis (OR = 1.153, p = 0.034)

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S2CID 52287975
Consistent with the role as a second hit, MAPK are known to be activated by oxidative stress and have been involved in APAP hepatotoxicity

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A similar trend was observed for SAM and SAH