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Moreover, SLE patients with renal involvement exhibited significantly higher serum KYN levels and KYN/TRP ratios than those without renal damage, suggesting that activation of the kynurenine pathway may exacerbate glomerular mesangial cell injury via pro-oxidative mechanisms [51] (Fig

Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant alpha-lipoic acid: A 3-week multicentre randomized controlled trial (ALADIN Study)

[DOI] [PMC free article] [PubMed] [Google Scholar] Green R

and LI, J.L

Participants were provided with either a placebo or a daily antioxidant bar containing high doses of vitamin C (343 mg) and vitamin E (84 mg) during a period of six months

[DOI] [PubMed] [Google Scholar] 329.Simons JF