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In one rabbit study, it improved wound contraction and formation of granular tissue, boosted antioxidant enzymes, and stimulated blood vessel development and growth

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In aging research, the compound provides a unique approach to investigating theories of metabolic decline, as NNMT expression increases with age in many tissues, potentially contributing to the NAD+ decline associated with aging processes

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A similar line of reasoning involves the kidney in the manifestations of the high-folatelow-vitamin B-12 interaction: depletion of serum vitamin B-12 may also be the result of preferential uptake of folic acid into the renal proximal tubule cells via FR-